NURS6630 week 4 Knowledge Check

Question 1 pts

Which dietary amino acid, when not broken down due to monoamine oxidase inhibition, is implicated in hypertensive crises in patients on MAOIs?

Group of answer choices

Tyramine

Tyrosine

Tryptophan

Histidine

Phenylalanine

Question 2 pts

In the physical examination of an adolescent with suspected depression, which of the following findings would be most likely?

Group of answer choices

Changes in blood pressure

Changes in weight

Changes in heart rate

Changes in respiratory rate

Changes in oxygen saturation

Question 3 pts

Which statement is TRUE?

Group of answer choices

Duloxetine is not recommended for diabetic neuropathy.

Tricyclic antidepressants have fewer side effects than selective serotonin reuptake inhibitors.

Amitriptyline is indicated for chronic pain.

Tricyclic antidepressants are rarely indicated in major depression.

Selegiline is often indicated for smoking cessation.

Question 4 pts

A patient with depression is prescribed amitriptyline. After starting the medication, the patient complains of dry mouth and constipation. These side effects are primarily due to which mechanism?

Group of answer choices

Dopamine antagonism

Histamine antagonism

Alpha-1 antagonism

Alpha-2 antagonism

Acetylcholine antagonism

Question 5 pts

What is a feature of tricyclic antidepressants?

Group of answer choices

Dialyzable

Lower seizure threshold

Insignificant first-pass metabolism

Low side effect profile

Low volume of distribution

question 6 Which monoamine oxidase inhibitor is matched with its mechanism of action?

Group of answer choices

Tranylcypromine: a selective MAO-B inhibitor

Hydracarbazine: a nonselective MAO-B inhibitor

Phenelzine: a selective MAO-A inhibitor

Moclobemide: a selective MAO-A inhibitor

Selegiline: a selective MAO-A inhibitor

NURS6630 week 4 Knowledge Check

Question 7 pts

Based on the amine hypothesis of depression, which hormonal change within the synaptic cleft is responsible for depression?

Group of answer choices

High levels of dopamine

Low levels of acetylcholine

High levels of serotonin

High levels of GABA

Low levels of norepinephrine

Question 8 pts

Which antidepressant is a suitable option for a patient concerned about sexual side effects?

Group of answer choices

Sertraline

Bupropion

Paroxetine

Escitalopram

Venlafaxine

Question 9 pts

Of the following list of tricyclic antidepressants, which medication is likely to have fewer side effects?

Group of answer choices

Desipramine

Duloxetine

Imipramine

Doxepin

Amitriptyline

Question 10 pts

Which monoamine oxidase inhibitor is matched with its mechanism of action?

Group of answer choices

Hydracarbazine: a selective MAO-B inhibitor

Selegiline: a MAO-B inhibitor

Phenelzine: a selective MAO-A inhibitor

Moclobemide: a non-selective MAOI

Tranylcypromine: a selective MAO-A inhibitor

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Solution: NURS6630 week 4 Knowledge Check

Question 1 pts

Which dietary amino acid, when not broken down due to monoamine oxidase inhibition, is implicated in hypertensive crises in patients on MAOIs?

Group of answer choices

Tyramine 

Tyrosine

Tryptophan

Histidine

Phenylalanine

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